The F.M. Kirby Neurobiology Center is fully committed to recruiting and supporting talented individuals and ensuring they all have a place in our research community.
September 2026
Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus.
MacKinnon S, Zacks R, Barry B, Mackey DA, Hunter DG, Engle EC, Whitman MC; Strabismus Genetics Research Consortium.
Ophthalmology. 2026 Sep;133(9):1099-1107. doi: 10.1016/j.ophtha.2026.05.016. Epub 2026 May 19.PMID: 42162761
Central sensitization: when is this the right terminology?
Hodges PW, Arendt-Nielsen L, Bannister K, Clauw D, Nijs J, van den Broeke E, Veasley C, Woolf CJ, Sterling M.
Pain. 2026 Sep 1;167(9):1986-1991. doi: 10.1097/j.pain.0000000000004017. Epub 2026 Jun 17.PMID: 42302106
Ultrastructural and Electrophysiological Determination of the Patency of Monkey Cone Outer Segment Membranes.
Paniagua AE, Volland S, Bryman GS, Luna G, Chang AW, Do MTH, Fisher SK, Williams DS.
J Neurosci. 2026 Sep 9;46(36):e0245262026. doi: 10.1523/JNEUROSCI.0245-26.2026.PMID: 42547447
Development of a human iPSC and patient phenotyping resource for preclinical investigations of neurodevelopmental disorders.
Chen C, Afshar-Saber W, Iglesias I, Kim K, Lewis B, Srinivasan G, Chen C, Hirsh R, Guardado R, Polanco T, Swanson A, Norabuena E, Whye D, Jain A, Cai C, Sun L, Chopra M, Chen I, Iannello G, Rozumny B, Hanson E, Sahin M, Buttermore ED.
Stem Cell Res. 2026 Sep;95:104073. doi: 10.1016/j.scr.2026.104073. Epub 2026 Aug 6.PMID: 42612424
Androgens mediate sexual dimorphism in Pilarowski-Bjornsson syndrome.
Anderson KJ, Thorolfsdottir ET, Nodelman IM, Halldorsdottir ST, Benonisdottir S, Alghamdi MA, Almontashiri NAM, Barry BJ, Begemann M, Britton JF, Burke S, Cogne B, Cohen ASA, de Diego Boguñá C, Eichler EE, Engle EC, Fahrner JA, Faivre L, Fradin M, Fuhrmann N, Gao CW, Garg G, Grečmalová D, Grippa M, Harris JR, Hoekzema K, Hershkovitz T, Hubbard S, Janssens K, Jurgens JA, Kmoch S, Knopp C, Koptagel MA, Ladha FA, Lapunzina P, Lindau T, Meuwissen M, Minicucci A, Neuhaus E, Nizon M, Nosková L, Park K, Patel C, Pfundt R, Prasun P, Rahner N, Robin NH, Ronspies C, Roohi J, Rosenfeld J, Saenz M, Saunders C, Stark Z, Thiffault I, Thull S, Velasco D, Velmans C, Verseput J, Vitobello A, Wang T, Weiss K, Wentzensen IM, Pilarowski G, Eysteinsson T, Gillentine M, Stefánsson K, Helgason A, Bowman GD, Bjornsson HT.
Am J Hum Genet. 2026 Sep 3;113(9):1946-1971. doi: 10.1016/j.ajhg.2026.08.005.PMID: 42692004
A single-nucleus transcriptomic atlas of human inner ear development.
van der Valk WH, Udayappan SD, van Beelen ESA, Goveia J, Beatovic A, Moisse M, Menafra R, de Groot JCMJ, Koehler KR, van Benthem PPG, Locher H.
Nat Neurosci. 2026 Sep 9. doi: 10.1038/s41593-026-02432-8. Online ahead of print.PMID: 42717251
Recurrent synapses between CO2-sensitive olfactory sensory neurons enable robust CO2 detection in Aedes aegypti mosquitoes.
Bao J, Alford W, Khandelwal A, Walsh L, Lantz G, Poncio S, Capdevila LS, Azatian Y, DePasquale B, Hildebrand DGC, Younger MA, Lee WA.
PLoS Biol. 2026 Sep 10;24(9):e3003959. doi: 10.1371/journal.pbio.3003959. eCollection 2026 Sep.PMID: 42721124
A de novo VPS16 missense variant blocks autophagic flux and extends DYT-VPS16 into infancy.
Gonzalez Saez-Diez E, Xue X, Ebrahimi-Fakhari D.
Autophagy Rep. 2026 Sep 9;5(1):2728539. doi: 10.1080/27694127.2026.2728539. eCollection 2026.PMID: 42730386
Morphogen-Directed, High-Throughput Development of hiPSC-Derived Telencephalic Organoids for Comparative In Vitro Phenotyping.
Whye D, Norabuena EM, Afshar-Saber W, Lewis B, Polanco TJ, Wood D, Sahin M, Buttermore ED.
urr Protoc. 2026 Sep;6(9):e70449. doi: 10.1002/cpz1.70449.PMID: 42747837
Divergence of Melanopsin’s Intrinsic Properties and Downstream Actions.
Viet NM, Caval-Holme FS, Milner ES, Johnson AS, Liu WW, Emanuel AJ, Do MTH.bioRxiv [Preprint]. 2026 Sep 15:2026.09.09.750349. doi: 10.64898/2026.09.09.750349.PMID: 42779720. Preprint.
Neurobehavioral outcomes following epilepsy surgery in tuberous sclerosis complex: A retrospective study.
Pearsson K, Selby M, Broekhuizen E, Pijs D, Stone S, Sahin M, Reilly C, Ailion A, Peters J.
Epilepsy Behav. 2026 Sep 28;185:111303. doi: 10.1016/j.yebeh.2026.111303. Online ahead of print.PMID: 42805032
Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model.
Vermudez SAD, Hameed MQ, Choe Y, McGinty GE, Liebhardt AM, Lin R, Hui B, Liang Y, Arce DJ, Lee HHC, Sahin M, Rotenberg A.
Epilepsia. 2026 Sep 30. doi: 10.1002/epi.70511. Online ahead of print.PMID: 42814106
September 2026
Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus.MacKinnon S, Zacks R, Barry B, Mackey DA, Hunter DG, Engle EC, Whitman MC; Strabismus Genetics Research Consortium.Ophthalmology. 2026 Sep;133(9):1099-1107. doi:...
August 2026
Movement Disorders in Aicardi-Goutières Syndrome and Response to Immunomodulation.Gonzalez Saez-Diez E, Ferrer Socorro M, Yang K, Battaglia N, Zaman Z, Bennett M, Vanderver A, Lee PY, Henderson LA, Andzelm MM, Ebrahimi-Fakhari D. Ann Clin Transl Neurol. 2026...
July 2026
Targeting Gi/o-coupled GPCRs to inhibit nociceptors: Insights from the serotonin receptor Htr1b and triptans.Peng J, Sanchez BT, Chirila AM, Zeng X, DeLisle MM, Qi L, Xiao JY, Lezgiyeva K, Low SA, Woolf CJ, Sharma N, Ginty DD. Cell Rep Med. 2026 Jul 30:102949. doi:...
June 2026
Loss of SARM1 Improves Phenotypes in a Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Ndiaye PS, Paul S, Zhao G, Ding C, Pulst SM, Schwarz T. Neurol Genet. 2026 Jun 9;12(4):e200400. doi: 10.1212/NXG.0000000000200400. eCollection 2026 Aug....
May 2026
DBSMatchMaker: Global Uptake and Insights from the First Year of a Collaborative Deep Brain Stimulation Platform. Rong J, Bernardi K, Ebrahimi-Fakhari D, Yang K. Mov Disord. 2026 May;41(5):1294-1298. doi: 10.1002/mds.70180. Epub 2026 Jan 8.PMID: 41503826 Bilateral...
April 2026
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome. Simon AJ, Picard N, d'Andrea V, Chang E, Leffler J, Centofante E, Taylor M, Bardi F, Cavicchiolo F, Hensch TK, Panzeri S, Chen C, Fagiolini M.Ann Clin Transl Neurol. 2026 Apr;13(4):700-713. doi:...
March 2026
Spectrum of Movement Disorders in Early-Onset Hereditary Spastic Paraplegia: A Study of 428 Cases. Resch D, Alecu JE, Yang K, Quiroz V, Schierbaum L, Bernardi K, Zaman Z, Agianda HAP, Rong J, Battaglia N, Carty S, Tam A, Kieslich M, Santorelli FM, González-Salazar C,...
February 2026
Comprehensive Clinical Characteristics, Longitudinal Adaptive Functioning, and Electroencephalogram Activity in MAPK8IP3-Related Neurodevelopmental Disorder. Sudnawa KK, Geltzeiler A, Kanner CH, Zreibe K, Pini N, Tam C, Fee RJ, Calamia S, Callejo E, Sharples H,...
January 2026
Electroencephalogram (EEG) Spike Metrics Discriminate Impending Epileptic Spasms From Other Seizures in Children With Tuberous Sclerosis Complex: A Pilot Study. Brandon Bravo Bruinsma PJ, Hadjinicolaou A, Rajaraman RR, Hussain SA, Krueger DA, Sahin M, Northrup H,...
June to December 2025
ap4b1 -/zebrafish demonstrate morphological and motor abnormalities. Hum Mol Genet. Ebrahimi-Fakhari Lab. Limited transmission of mixed convergent signals at the mouse retinogeniculate synapse. Neuron. Chen Lab. Structural and functional basis of mechanosensitive...
January to May 2025
Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders. Front Neuroscience. Human Neuron Core. Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT...
July to December 2024
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders. Genet Med. Engle Lab. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Cell Mol Life Sci. Woolf Lab. Dopamine biases...
May & June 2024
Spinal projecting neurons in rostral ventromedial medulla co-regulate motor and sympathetic tone. Cell. Zhigang He Lab. The spectrum of movement disorders in young children with ARX-related epilepsy-dyskinesia syndrome. Ann Clin Transl Neurol. Ebrahimi-Fakhari Lab....
March & April 2024
Neural and behavioural state switching during hippocampal dentate spikes. Nature. Farrell Lab. Presence of Copy Number Variants Associated With Esotropia in Patients With Exotropia. JAMA Ophthalmol. Engle & Whitman Labs. Comprehensive phenotypes of patients with...
January & February 2024
Quantitative profiling of posttranslational modifications of pathological tau via sarkosyl fractionation and mass spectrometry. Nature Protocols. Steen Lab. High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal...
November & December 2023
A transcriptomic taxonomy of mouse brain-wide spinal projecting neurons. Nature. Z. He Lab. Clinical Variants Paired with Phenotype: A Rich Resource for Brain Gene Curation. Genetics in Medicine. Chopra & Sahin Labs. The Multistable Melanopsins of Mammals....
September & October 2023
Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity. Science Advances. Lipton Lab. Shortened Motor Evoked Potential Latency in the Epileptic Hemisphere of Children With Focal Epilepsy. Journal of Clinical Neurophysiology. Rotenberg Lab. Behavioral...
July & August 2023
The projection-specific signals that establish functionally segregated dopaminergic synapses. Cell. Umemori Lab. Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nature...
May & June 2023
Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nature Genetics. Engle Lab. Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal...
March & April 2023
A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages. Cells. Woolf Lab. Epilepsy Severity Is Associated With Head Circumference and Growth Rate in Infants With Tuberous Sclerosis Complex. Pediatric Neurology. Sahin Lab....
January & February 2023
CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility. Molecular Psychiatry. Fagiolini & Umemori Labs. Common mouse models of tauopathy reflect early but not late human disease. Molecular Neurodegeneration. Steen Lab Cross-talk...
July – December 2022
Structured cerebellar connectivity supports resilient pattern separation. Nature. Lee Lab. DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting. Cell Reports. Sahin Lab. Core transcription programs controlling...
January – June 2022
Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells. Neuron. Z. He Lab. Automated preclinical detection of mechanical pain hypersensitivity and analgesia. Pain. Woolf Lab. ASD/OCD-Linked Protocaherin-10...
November & December 2021
Posttranslational Modifications Mediate the Structural Diversity of Taupathy Strains. Cell. Steen Lab. Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus. Frontiers in Cellular Neuroscience. Rosenberg Lab. A multiparametric...
September & October 2021
Nuclear IMPDH Filaments in Human Gliomas. Journal of Neuropathology & Experimental Neurology. Engle Lab. Functional architecture of neural circuits for leg proprioception in Drosophila. Cell Press. Lee Lab. Retinal Ganglion Cell Axon Regeneration Requires...