Loss of SARM1 Improves Phenotypes in a Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Ndiaye PS, Paul S, Zhao G, Ding C, Pulst SM, Schwarz T. Neurol Genet. 2026 Jun 9;12(4):e200400. doi: 10.1212/NXG.0000000000200400. eCollection 2026 Aug. PMID: 42290675
De novo VPS16 missense variant causes infantile-onset dystonia with defective autophagic flux. Gonzalez Saez-Diez E, Xue X, Tam A, Kim HM, Carty S, Rong J, Ferrer-Socorro M, Yang K, Ebrahimi-Fakhari D. JCI Insight. 2026 Jun 30:e207998. doi: 10.1172/jci.insight.207998. Online ahead of print.PMID: 42378062
Derivation of elephant induced pluripotent stem cells. Appleton E, Korover N, Hong K, Ambriz-Peña X, Tanaka Y, Ashkenazy-Titelman A, Rasmussen-Ivey C, Rodríguez-Caycedo C, Bhide K, Bai H, Queiroz A, Nelson JW, Rathod G, Morgan M, Mastracci A, Nelson TM, Knox G, McNutt B, Malviya N, Zhang K, Kowalczyk A, Bow A, McLendon B, Slamecka J, Ryon K, Proszynski J, Houerbi N, Kleinman AS, Poon CL, Kiso W, James M, Park IH, Gray C, Pearson VR, Mason CE, Cantarel BL, Koehler KR, Shapiro B, Kehler J, Lamm B, Church G, Hysolli E. Nat Methods. 2026 Jun 22. doi: 10.1038/s41592-026-03136-4. Online ahead of print.PMID: 42332088
Central sensitization: when is this the right terminology? Hodges PW, Arendt-Nielsen L, Bannister K, Clauw D, Nijs J, van den Broeke E, Veasley C, Woolf CJ, Sterling M. Pain. 2026 Jun 17. doi: 10.1097/j.pain.0000000000004017. Online ahead of print.PMID: 42302106
Schizophrenia-associated glycoprotein Adamtsl3 regulates perineuronal net formation, maintenance, and adult cortical plasticity. Cramer TML, Hannan SB, Petre L, Bear MF, Hensch TK, Tyagarajan SK. Mol Psychiatry. 2026 Jun 11. doi: 10.1038/s41380-026-03672-7. Online ahead of print.PMID: 42277231
Distributed control circuits across a brain-and-cord connectome. Bates AS, Phelps JS, Kim M, Yang HH, Matsliah A, Ajabi Z, Perlman E, Delgado KM, Osman MAM, Salmon CK, Gager J, Silverman B, Renauld S, Salman F, Patel J, Collie MF, Fan J, Pacheco DA, Zhao Y, Zhang W, Capdevila LS, Roberts RJV, Munnelly EJ, Griggs N, Langley H, Moya-Llamas B, Zhang Z, Maloney RT, Yu SC, Sterling AR, Sorek M, Kruk K, Serafetinidis N, Dhawan S, Klemm F, Brooks P, Lesser E, Jones JM, Pierce-Lundgren SE, Lee SY, Luo Y, Cook AP, McKim TH, Giakoumas DS, Gorko B, Ellis-Joyce J, Zhang J, Kophs EC, Falt T, Negron-Morales AM, Burke A, Hebditch J, Willie KP, Willie R, Popovych S, Kemnitz N, Ih D, Lee K, Lu R, Halageri A, Bae JA, Jourdan B, Schwartzman G, Demarest DD, Behnke E, Bland D, Kristiansen A, Skelton J, Stocks T, Garner D, Hernandez A, Kumar S; BANC-FlyWire Consortium; Daly KC, Dorkenwald S, Collman F, Suver MP, Fenk LM, Pankratz MJ, Yao Z, Wang F, Huston SJ, Stürner T, Jefferis GSXE, Eichler K, Seeds AM, Hampel S, Agrawal S, Okubo TS, Zandawala M, Macrina T, Adjavon DY, Funke J, Tuthill JC, Azevedo A, Seung HS, de Bivort BL, Murthy M, Drugowitsch J, Wilson RI, Lee WA. Nature. 2026 Jun 8. doi: 10.1038/s41586-026-10735-w. Online ahead of print.PMID: 42259917
High-Fidelity Backpropagation through Primate Foveal Cones. Wienbar SR, Bryman GS, Do MTH. J Neurosci. 2026 Jun 3;46(22):e0085262026. doi: 10.1523/JNEUROSCI.0085-26.2026.PMID: 42049512
The Wnt inhibitor Tiki2 maintains articular cartilage homeostasis and protects against osteoarthritis. Li X, Zhao W, MacDonald BT, Zhang H, Duan W, Xu K, He X, Zhang X. Sci Signal. 2026 Jun 2;19(940):eadv0789. doi: 10.1126/scisignal.adv0789. Epub 2026 Jun 2.PMID: 42228772
ACMG/AMP variant classification specifications from the ClinGen Epilepsy Sodium Channel Variant Curation Expert Panel. Smith L, Bonkowski E, Prentice A, Cohen S, Lusk L, Parthasarathy S, Burns B, Butler E, Chen Y, Dady K, Dugger S, Ing A, Lassiter R, Lewis-Smith D, Mulhern M, Nguyen JNH, Olival J, Sajan SA, Thompson CH, George AL Jr, Wagnon J, Yergert K, Magielski JH, McKee JL, Riggs E, Wiltrout K, Poduri A, Helbig I, Mefford HC. Genet Med. 2026 Jun 1:102615. doi: 10.1016/j.gim.2026.102615. Online ahead of print.PMID: 42227234
Autism subtypes identified using cross-species functional connectivity analyses. Pagani M, Zerbi V, Gini S, Alvino FG, Banerjee A, Barberis A, Basson MA, Bozzi Y, Galbusera A, Ellegood J, Fagiolini M, Lerch JP, Matteoli M, Montani C, Pozzi D, Provenzano G, Scattoni ML, Wenderoth N, Xu T, Lombardo MV, Milham MP, Di Martino A, Gozzi A. Nat Neurosci. 2026 Jun;29(6):1476-1487. doi: 10.1038/s41593-026-02287-z. Epub 2026 May 15.PMID: 42141307
Precision Antisense Oligonucleotide Therapy Amenability for Infantile Genetic Epilepsies. Sherrill E, Cheerie D, Beck CJ, Whittle EF, Shafi Y, Chandler NJ, Christodoulou J, Daniel J, Hassell J, Lachgar-Ruiz M, Mulhern S, Scotchman E, Sidhu J, Tedja CF, Chitty LS, Cross JH, Scheffer IE, Zhou H, Yu TW, Chau V, Stephenson SEM, Poduri A, Howell KB, McTague A, Costain G, D’Gama AM; Gene-STEPS Study Group. JAMA Neurol. 2026 Jun 1;83(6):598-601. doi: 10.1001/jamaneurol.2026.1021.PMID: 42081236
Early Vigabatrin Treatment Before Seizure Onset Decreased Interictal Epileptiform Discharges Over the Duration of the PREVeNT Study. McPherson TO, Bebin EM, Farach LS, Wulsin AC, Davis P, Au KS, Sahin M, Wu JY, Taub KS, Rajaraman R, Randle S, McClintock WM, Koenig MK, Frost MD, Northrup H, Werner K, Nolan D, Wong M, Krefting J, Peri K, Cutter G, Krueger D, Peters JM, Porter BE; PREVeNT Study Group. Pediatr Neurol. 2026 Jun;179:30-36. doi: 10.1016/j.pediatrneurol.2026.03.005. Epub 2026 Mar 11.PMID: 41904855
A patient with a rare metabolic disease and myo-inositol administration leading to a new treatment for epilepsy. Berry GT, Vos EN, Demirbas D, Brucker W, Gilmartin A, Lehtinen MK, Yang E, Prabhu SP, Chen J, Huang X, Qi W, Bennett MJ, Haynes RL, Rodan L, Poduri A, Pearl PL, Rotenberg A, He M, Rubio-Gozalbo ME. Mol Genet Metab. 2026 Jun;148(2):109871. doi: 10.1016/j.ymgme.2026.109871. Epub 2026 Mar 3.PMID: 41875761
Interictal cardiac repolarization abnormalities improve after surgical seizure resolution in pediatric drug-resistant epilepsy. Bozdag E, Makaram N, Sabino G, Bolton J, Grant EP, Rotenberg A, Tamilia E. Epilepsia. 2026 Jun;67(6):3034-3047. doi: 10.1002/epi.70206. Epub 2026 Mar 18.PMID: 41848583
Human induced pluripotent stem cell-derived inner ear organoids reveal hair cell damage and plasticity after cisplatin and gentamicin exposure. Lucassen AWA, van den Boogaard WMC, Fousert E, Zhang J, Koehler KR, de Groot JCMJ, van Benthem PPG, van der Valk WH, Locher H. Dis Model Mech. 2026 Jun 1;19(6):dmm052511. doi: 10.1242/dmm.052511. Epub 2026 Mar 3.PMID: 41773293
Expanding Clinical Experience With Istradefylline in ADCY5-Related Movement Disorder: A Case With No Benefit. Bernardi K, Ebrahimi-Fakhari D, Yang K. Mov Disord Clin Pract. 2026 Jun;13(6):1582-1583. doi: 10.1002/mdc3.70572. Epub 2026 Feb 25.PMID: 41741127
The Infant and Toddler Developmental Profile of Kleefstra Syndrome. Yue SL, Pillai RLI, Frazier Z, Osika H, Quinn M, O’Toole J, Heslin B, Zhang B, Dies KA, Pais L, O’Donnell-Luria A, Horlbeck MA, Kossowsky J, Lipton J, Srivastava S. Am J Med Genet A. 2026 Jun;200(6):1267-1272. doi: 10.1002/ajmga.70071. Epub 2026 Feb 6.PMID: 41652658
Multimodality Craniofacial Phenotyping of Congenital Facial Weakness Disorders. Almpani K, Devine KR, Liberton DK, Mishra R, Bassim C, Van Ryzin C, Facio FM, Webb BD, Barry BJ, Engle EC, Wang Jabs E, Collins FS, Manoli I, Lee JS; Moebius Syndrome Research Consortium. Cleft Palate Craniofac J. 2026 Jun;63(6):1455-1468. doi: 10.1177/10556656251344128. Epub 2025 Jul 3.PMID: 40611650
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