The F.M. Kirby Neurobiology Center is fully committed to recruiting and supporting the full spectrum of our diverse population and ensuring that everybody has a place in our research community.
March & April 2024
Neural and behavioural state switching during hippocampal dentate spikes. Nature. Farrell Lab.
Presence of Copy Number Variants Associated With Esotropia in Patients With Exotropia. JAMA Ophthalmol. Engle & Whitman Labs.
Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism. Epilepsia. Poduri Lab.
CSMD1 regulates brain complement activity and circuit development. Brain Behav Immun. Stevens Labs.
TMC function, dysfunction, and restoration in mouse vestibular organs. Frontiers in Neurology. Holt/Geleoc Lab.
Embryonic microglia maintain the brain’s cortical fault lines. Trends Immunology. Stevens Lab.
Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls. Stem Cell Res. Sahin Lab.
March & April 2024
Neural and behavioural state switching during hippocampal dentate spikes. Nature. Farrell Lab. Presence of Copy Number Variants Associated With Esotropia in Patients With Exotropia. JAMA Ophthalmol. Engle & Whitman Labs. Comprehensive phenotypes of patients with...
January & February 2024
Quantitative profiling of posttranslational modifications of pathological tau via sarkosyl fractionation and mass spectrometry. Nature Protocols. Steen Lab. High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal...
November & December 2023
A transcriptomic taxonomy of mouse brain-wide spinal projecting neurons. Nature. Z. He Lab. Clinical Variants Paired with Phenotype: A Rich Resource for Brain Gene Curation. Genetics in Medicine. Chopra & Sahin Labs. The Multistable Melanopsins of Mammals....
September & October 2023
Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity. Science Advances. Lipton Lab. Shortened Motor Evoked Potential Latency in the Epileptic Hemisphere of Children With Focal Epilepsy. Journal of Clinical Neurophysiology. Rotenberg Lab. Behavioral...
July & August 2023
The projection-specific signals that establish functionally segregated dopaminergic synapses. Cell. Umemori Lab. Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nature...
May & June 2023
Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nature Genetics. Engle Lab. Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal...
March & April 2023
A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages. Cells. Woolf Lab. Epilepsy Severity Is Associated With Head Circumference and Growth Rate in Infants With Tuberous Sclerosis Complex. Pediatric Neurology. Sahin Lab....
January & February 2023
CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility. Molecular Psychiatry. Fagiolini & Umemori Labs. Common mouse models of tauopathy reflect early but not late human disease. Molecular Neurodegeneration. Steen Lab Cross-talk...
July – December 2022
Structured cerebellar connectivity supports resilient pattern separation. Nature. Lee Lab. DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting. Cell Reports. Sahin Lab. Core transcription programs controlling...
January – June 2022
Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells. Neuron. Z. He Lab. Automated preclinical detection of mechanical pain hypersensitivity and analgesia. Pain. Woolf Lab. ASD/OCD-Linked Protocaherin-10...
November & December 2021
Posttranslational Modifications Mediate the Structural Diversity of Taupathy Strains. Cell. Steen Lab. Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus. Frontiers in Cellular Neuroscience. Rosenberg Lab. A multiparametric...
September & October 2021
Nuclear IMPDH Filaments in Human Gliomas. Journal of Neuropathology & Experimental Neurology. Engle Lab. Functional architecture of neural circuits for leg proprioception in Drosophila. Cell Press. Lee Lab. Retinal Ganglion Cell Axon Regeneration Requires...